Endocannabinoids Mediate Synaptic Plasticity at Mixed Synapses
نویسندگان
چکیده
Endocannabinoids are generally known to suppress excitatory or inhibitory synaptic transmission. Now, in an elegant series of experiments, Cachope et al. reveal a novel signaling pathway whereby endocannabinoids indirectly potentiate mixed chemical and electrical synapses. Gap junction-mediated transmission can thus be potentiated via distinct frequency-dependent mechanisms.
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عنوان ژورنال:
- Neuron
دوره 56 شماره
صفحات -
تاریخ انتشار 2007